The effect of concurrent infections with Pasteurella multocida and Ascaridia galli on free range chickens
The effect of concurrent infections with Pasteurella multocida and Ascaridia galli on free range chickens
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DOI：
10.1016/s0378-1135(02)00015-9
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发表时间：
2002-05-24
影响因子：
3.3
通讯作者：
Jensen, AL
中科院分区：
文献类型：
--
作者：
Dahl, C;Permin, A;Jensen, AL
在丹麦的散养鸡中观察到多杀性巴氏杆菌和鸡蛔虫的患病率很高，但其影响尚不清楚。开展了一项研究，旨在检验鸡内鸡原菌和多杀性巴氏杆菌之间的相互作用以及对生产的影响。五组，每组 20 只 18 周龄的 Lohmann Brown 鸡被感染。 I 组经口感染 1000 +/- 50 个含胚鸡鸡卵。第 2 组获得 10(4) cfu p。气管内多杀性。第 3 组感染了鸡原体，随后感染了多杀性巴氏杆菌。第 4 组感染了多杀性疟原虫，随后感染了鸡原体。第 5 组是对照组。该研究持续了 11 周，记录了临床表现、体重增加和产蛋量。多杀性巴氏杆菌的排泄量根据个体进行测定，并进行血涂片进行分类计数。研究结束时，记录病理病变以及粪便中成虫、幼虫和虫卵的数量。与分别感染鸡鸡或多杀性疟原虫相比，感染两种病原体时，鸟类受到的影响更为严重。双重感染时观察到体重增加和产蛋量较低。 A. galli 感染继发继发性多杀性 P. multocida 感染，导致更多禽类出现病理损伤，并持续排出多杀性 P. multocida。 总之，观察到 A. galli 和 R multocida 之间存在负相互作用，并推测散养鸡在感染 A. galli 时发生禽霍乱暴发的风险更高。 (C) 2002 Elsevier Science B.V. 保留所有权利。
Pasteurella multocida and Ascaridia galli are observed with high prevalences in free range chickens in Denmark, but the impact is unknown. A study was carried out to examine the interaction between A. galli and P. multocida in chickens and the impact on production.Five groups, each with 20 18-week-old Lohmann Brown chickens were infected. Group I was orally infected with 1000 +/- 50 embryonated A. galli eggs. Group 2 received 10(4) cfu p. multocida intratracheally. Group 3 was infected with A. galli and subsequently with P. multocida. Group 4 was infected with P. multocida followed by A. galli. Group 5 was the control. The study ran for I I weeks where clinical manifestations, weight gain and egg production were recorded. Excretion of P. multocida was determined on individual basis and blood smears were made for differential counts. At the end of the study pathological lesions and the number of adult worms, larvae and eggs in the faeces were recorded.The birds were more severely affected when infected with both pathogens compared to single infections with A. galli or P. multocida, respectively. A lower weight gain and egg production was observed with dual infections. A. galli infection followed by a secondary P. multocida infection resulted in more birds with pathological lesions and continued P. multocida excretion.In conclusion a negative interaction between A. galli and R multocida was observed and it is postulated that free range chickens are at higher risk of being subjected to outbreaks of fowl cholera when they are infected with A. galli. (C) 2002 Elsevier Science B.V. All rights reserved.