Some assembly required: Redefining the mitotic checkpoint.
Some assembly required: Redefining the mitotic checkpoint.
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DOI：
10.1080/23723556.2017.1314238
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发表时间：
2017
影响因子：
2.1
通讯作者：
Millar JBA
中科院分区：
文献类型：
--
作者：
Meadows JC;Millar JBA
纺锤体组装检查点（也称为纺锤体或有丝分裂检查点）是确保染色体分离保真度的监视系统。在这里，我们建议，根据历史和最近的证据，该信号系统通过两条不同但功能重叠的途径监测着丝粒附着和纺锤体组装。
The spindle assembly checkpoint (also known as the spindle or mitotic checkpoint) is a surveillance system that ensures fidelity of chromosome segregation. Here we suggest, in light of historical and more recent evidence, that this signaling system monitors kinetochore attachment and spindle assembly by two distinct, but functionally overlapping, pathways.