A methodologic study of histologic classification and grading of malignancy in oral squamous cell carcinoma.
A methodologic study of histologic classification and grading of malignancy in oral squamous cell carcinoma.
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口腔鳞状细胞癌恶性肿瘤组织学分类和分级的方法学研究。
DOI：
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发表时间：
1984
期刊：
影响因子：
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通讯作者：
L. S. Hansen
中科院分区：
文献类型：
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作者：
G. Anneroth;L. S. Hansen
本文设计了一个多因素分级系统，用于舌和口底癌的组织学分类和恶性程度的分级。该系统提出了所有形态变量的定义和说明。对52例鳞状细胞癌分类的统计分析表明，由两个独立观察者对所有形态学变量进行的系统的重现性良好。平均总恶性肿瘤、肿瘤细胞群和肿瘤-宿主关系评分与所有不同形态参数的平均评分显示出统计学显着相关性，但某些特定例外情况除外。探讨了以往分级制度的历史技术和理论错误的例外和缺乏相关性的原因。
A multifactorial grading system was devised for the histologic classification and grading of malignancy in carcinoma of tongue and floor of mouth. The system is presented with all morphologic variables defined and illustrated. Statistical analysis of the classification of 52 cases of squamous cell carcinoma revealed that the reproducibility of the system by two independent observers was good for all morphologic variables. Mean total malignancy, tumor cell population, and tumor-host relationship scores showed statistically significant correlations with mean ratings for all the different morphologic parameters, with certain specified exceptions. Reasons for the exceptions and lack of correlation of the histotechnical and theoretical errors of previous grading systems are explored.