Navigating a research partnership between academia and industry to assess the impact of personalized genetic testing.
Navigating a research partnership between academia and industry to assess the impact of personalized genetic testing.
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DOI：
10.1038/gim.2011.59
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发表时间：
2012-02
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描述学术研究人员和两家个性化基因检测公司之间建立伙伴关系的过程，这些公司将管理利益冲突，同时允许研究人员研究这个新兴行业的影响。我们制定了一个透明的过程，持续沟通所有研究合作伙伴的利益，以解决在建立研究目标，调查开发，数据收集，分析和手稿准备的挑战。利用现有的文献利益冲突和我们的经验，我们创建了一个清单，为学术和行业研究人员寻求结构的研究伙伴关系。我们的清单包括有关研究参与者的风险，研究的赞助，数据分析的控制，发表结果的自由，研究对行业客户的影响，对所有合作伙伴的开放性，在出版前共享结果以及出版行业特定数据的问题。透明度对于在伙伴之间建立信任至关重要。让所有合作伙伴参与研究开发提高了我们的研究质量，并提供了在研究过程早期管理冲突的机会。学术界和工业界之间的关系是复杂的，需要透明和回应所有人关切的战略。在开始研究伙伴关系之前使用问题清单可能有助于管理利益冲突。
To describe the process of structuring a partnership between academic researchers and two personalized genetic testing companies that would manage conflicts of interest while allowing researchers to study the impact of this nascent industry. We developed a transparent process of ongoing communication about the interests of all research partners to address challenges in establishing study goals, survey development, data collection, analysis, and manuscript preparation. Using the existing literature on conflicts of interest and our experience, we created a checklist for academic and industry researchers seeking to structure research partnerships. Our checklist includes questions about the risk to research participants, sponsorship of the study, control of data analysis, freedom to publish results, the impact of the research on industry customers, openness to input from all partners, sharing results before publication, and publication of industry-specific data. Transparency is critical to building trust between partners. Involving all partners in the research development enhanced the quality of our research and provided an opportunity to manage conflicts early in the research process. Navigating relationships between academia and industry is complex and requires strategies that are transparent and responsive to the concerns of all. Employing a checklist of questions prior to beginning a research partnership may help to manage conflicts of interest.