Actin polymerization is not required for the fast block to polyspermy in the African clawed frog, Xenopus laevis.
Actin polymerization is not required for the fast block to polyspermy in the African clawed frog, Xenopus laevis.
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DOI:
10.17912/micropub.biology.000365
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发表时间:
2021-02-09
影响因子:
--
通讯作者:
Carlson AE
中科院分区:
文献类型:
--
作者:
Tembo M;Sauer ML;Wisner BW;Beleny DO;Napolitano MA;Carlson AE
Fertilization of an egg by multiple sperm presents one of the earliest and most prevalent obstacles to successful reproduction. Eggs employ multiple mechanisms to prevent sperm entry into the nascent zygote. The fast block to polyspermy uses a depolarization to inhibit sperm entry. For some external fertilizers, fertilization and the fast block require actin polymerization. Here we explored whether the fast block to polyspermy in the external fertilizer, Xenopus laevis, requires actin polymerization. Inseminating in the presence of inhibitor cytochalasin B, here we demonstrate that actin polymerization is not required for the fast block to polyspermy in X. laevis.