No pain, no gain: Sensory neurons heal a sunburn.
No pain, no gain: Sensory neurons heal a sunburn.
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DOI:
10.1016/j.immuni.2021.06.011
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发表时间:
2021-07-13
期刊:
影响因子:
32.4
通讯作者:
Sokol CL
中科院分区:
文献类型:
--
作者:
Flayer CH;Sokol CL
In a recent issue of Nature, Hoeffel et al. describe a novel pathway of sterile tissue repair utilizing a mouse model of sunburn. This wound healing pathway is coordinated by sensory neuron-derived TAFA4 that induces IL-10 production from Tim4+ dermal macrophages to prevent sustained inflammation and the emergence of tissue fibrosis.
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