Asymmetric Michael addition of nitroalkanes to nitroalkenes catalyzed by C2-symmetric tridentate bis(oxazoline) and bis(thiazoline) zinc complexes
Asymmetric Michael addition of nitroalkanes to nitroalkenes catalyzed by C2-symmetric tridentate bis(oxazoline) and bis(thiazoline) zinc complexes
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DOI：
10.1021/ja0604008
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发表时间：
2006-06-14
影响因子：
15
通讯作者：
Zhang, Shi-Wei
中科院分区：
文献类型：
--
作者：
Lu, Shao-Feng;Du, Da-Ming;Zhang, Shi-Wei
在c2对称手性三齿双（恶唑啉）和双（噻唑啉）锌配合物催化下，通过在硝基烯烃上加成硝基烷烃，首次实现了1,3-二硝基化合物的不对称合成，其对映选择性高（高达95% ee）。
The first asymmetric synthesis of 1,3-dinitro compounds through Michael addition of nitroalkanes to nitroalkenes catalyzed byC2-symmetric chiral tridentate bis(oxazoline) and bis(thiazoline) zinc complexes was achieved with high enantioselectivities (up to 95% ee).