Assessing a minimal executive operation in schizophrenia
Assessing a minimal executive operation in schizophrenia
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DOI：
10.1016/j.psychres.2005.07.001
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发表时间：
2005-11-15
影响因子：
11.3
通讯作者：
Huron, C
中科院分区：
文献类型：
--
作者：
Grillon, ML;Johnson, MK;Huron, C
对 24 名精神分裂症患者和 24 名正常对照者进行了对刚刚看到的刺激（刷新）的思考的最小认知操作的研究。当参与者阅读一个单词、立即再次阅读一个单词或在该单词不再出现后刷新该单词时，测量了言语反应时间。患者在第二次阅读单词时表现出与对照组相同的启动能力，并且仅在刷新条件下比对照组慢于说出单词。在一项惊喜测试中，参与者被要求识别他们以前见过的单词，并根据他们是否基于有意识的回忆、熟悉或猜测来识别单词，并给出记住、知道或猜测的答案。尽管患者总体上表现出较差的识别记忆，但刷新对长期记忆准确性和记住反应的有益影响得以保留，而他们从看到一个项目两次而获得的熟悉度方面的好处比刷新它要少。这些结果表明，尽管患者可能在恢复过程中遇到一些困难，但在诱导下这样做时，他们会表现出显着的长期记忆益处。 (c) 2005 Elsevier Ireland Ltd. 保留所有权利。
The minimal cognitive operation of thinking of a just-seen stimulus (refreshing) was studied in 24 patients with schizophrenia and 24 normal controls. Verbal response times were measured when participants read a word, read a word immediately again, or refreshed a word just after it was no longer present. Patients showed equal priming as controls in reading a word for the second time and were slower than controls to say a word only in the refresh condition. On a surprise test, participants were asked to recognize the words they had seen previously and to give Remember, Know, or Guess responses according to whether they recognized words on the basis of conscious recollection, familiarity, or guessing. Although patients showed overall poorer recognition memory, the beneficial effect of refreshing on long-term memory accuracy and Remember responses was preserved, whereas they derived less benefit in familiarity from seeing an item twice than from refreshing it. These results suggest that although patients may have some difficulty engaging the refresh process, they show significant long-term memory benefits when induced to do so. (c) 2005 Elsevier Ireland Ltd. All rights reserved.