Topical tranexamic acid versus hot saline for field quality during endoscopic sinus surgery
Topical tranexamic acid versus hot saline for field quality during endoscopic sinus surgery
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DOI：
10.4103/1012-5574.144965
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发表时间：
2014-10-01
影响因子：
0.4
通讯作者：
Abd-El-Fattah, Mohammed Hamed
中科院分区：
文献类型：
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作者：
Shehata, Ahmed;Ibrahim, Mohammed Sabra;Abd-El-Fattah, Mohammed Hamed
ObjectivesThis study conducted to evaluate and comparison between topical氨甲环酸（TA）and hot saline as a alternative to local vasoconstrictor on bleeding and surgery site quality during endoscopic sinus surgery（FESS.Patients and MethodsThis study was performed on 75 patients with I and II class of American society of anesthesia（A.S.A.），在全身麻醉下进行择期FESS。患者分为三组，每一组（25例），A组：局部氨甲环酸（1000毫克稀释在20毫升生理盐水）是在手术过程中使用的包装和冲洗，B组：热盐水高达50摄氏度使用和C组：（对照组）生理盐水used.ResultsThe使用局部（TA）与估计失血量214.2毫升显着减少比局部热盐水，这是216.75，都比生理盐水，这是272.66更好。此外（TA）和热盐水显示减少手术的持续时间，提高手术野质量和盲目的外科医生满意度相比，与control group.ConclusionThe使用局部TA和局部热盐水高达50摄氏度实现减少失血，手术时间和提高手术野质量在FESS。
ObjectivesThis study conducted to evaluate and compare between topical tranexamic acid (TA) and hot saline as an alternative to local vasoconstrictors on bleeding and surgery site quality during endoscopic sinus surgery (FESS).Patients and methodsThis study was performed on 75 patients with class I and II American society of anesthesiologists (A.S.A.), scheduled for elective FESS under general anesthesia. Patients divided into three groups, each (25 patients), group A: topical tranexamic acid (1000mg diluted in 20ml normal saline) was used during surgery for packing and irrigation, group B: hot saline up to 50 degrees C was used and group C :(control group) normal saline was used.ResultsThe use of local (TA) was associated with significant decrease in estimated blood loss 214.2 ml more than local hot saline which was 216.75 and both is much better than the normal saline which was 272.66. Also (TA) and hot saline showed decrease in the duration of surgery, improve the surgical field quality and blinded surgeon satisfaction as compared with the control group.ConclusionThe use of local TA and local hot saline up to 50 degrees C achieved reduction in blood loss, duration of surgery and improved surgical field quality during FESS.