An ECG simulator for generating maternal-foetal activity mixtures on abdominal ECG recordings
An ECG simulator for generating maternal-foetal activity mixtures on abdominal ECG recordings
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DOI：
10.1088/0967-3334/35/8/1537
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发表时间：
2014-08-01
影响因子：
3.2
通讯作者：
Clifford, Gari D.
中科院分区：
文献类型：
--
作者：
Behar, Joachim;Andreotti, Fernando;Clifford, Gari D.
从非侵入式传感器中准确提取胎儿心电图（FECG）形态仍然是一个悬而未决的问题。部分原因是缺乏可用的公共数据库。即使当金标准的信息（即来自头皮电极）是存在的，FECG的收集可能是有问题的，特别是在紧张或临床上重要的事件。为了解决这个问题，我们已经介绍了一个FECG模拟器的基础上，早期的工作胎儿和成人ECG建模。开源胎儿ECG合成模拟器fecgsyn能够生成具有真实幅度、形态、心跳间变异性、心率变化和噪声的母胎ECG混合物。由于呼吸、胎儿活动和子宫收缩，胎儿和母体心脏的位置（旋转和旋转相关）运动也被添加到模拟器中。该模拟器用于生成2013年心脏病学挑战数据集PhysioNet Computing的部分信号，并已发布在Physionet上。org（以及生成真实场景的脚本）。该工具箱使该领域的进一步研究成为可能，并为罕见病理情况的行业和监管测试提供了部分标准。
Accurate foetal electrocardiogram (FECG) morphology extraction from non-invasive sensors remains an open problem. This is partly due to the paucity of available public databases. Even when gold standard information (i.e derived from the scalp electrode) is present, the collection of FECG can be problematic, particularly during stressful or clinically important events.In order to address this problem we have introduced an FECG simulator based on earlier work on foetal and adult ECG modelling. The open source foetal ECG synthetic simulator, fecgsyn, is able to generate maternal-foetal ECG mixtures with realistic amplitudes, morphology, beat-to-beat variability, heart rate changes and noise. Positional (rotation and translation-related) movements in the foetal and maternal heart due to respiration, foetal activity and uterine contractions were also added to the simulator.The simulator was used to generate some of the signals that were part of the 2013 PhysioNet Computing in Cardiology Challenge dataset and has been posted on Physionet. org (together with scripts to generate realistic scenarios) under an open source license. The toolbox enables further research in the field and provides part of a standard for industry and regulatory testing of rare pathological scenarios.