Sequence analyses of herpesviral enzymes suggest an ancient origin for human sexual behavior.
Sequence analyses of herpesviral enzymes suggest an ancient origin for human sexual behavior.
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疱疹病毒酶的序列分析表明人类性行为的古老起源。
DOI：
10.1073/pnas.85.8.2658
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发表时间：
1988
影响因子：
11.1
通讯作者：
Nevins,R
中科院分区：
文献类型：
--
作者：
Gentry,GA;Lowe,M;Alford,G;Nevins,R
单纯疱疹病毒（HSV）和绒猴疱疹病毒（MHV）的脱氧胸苷激酶的氨基酸序列的比较表明，HSV-1和HSV-2的分歧时间为800万至1000万年前。与MHV一样，HSV-1和HSV-2在其天然宿主中引起局部感染，并且在短暂的传染期内需要两个个体之间的直接接触才能传播。由于B病毒是HSV的近亲，依赖于口腔和生殖器两种传播途径，我们假设祖先HSV（aHSV）是相似的，并且对于HSV-1和HSV-2来说，生殖器和口腔部位必须在微生物学上彼此隔离，而口腔-口腔和生殖器-生殖器接触必须促进以维持两种aHSV毒株。我们认为，获得持续的性吸引力的祖先人类女性和采用近面对面交配，人类性行为的两个标志，提供了分歧的条件。
Comparison of the amino acid sequences of the deoxythymidine kinases of herpes simplex (HSV) and of marmoset herpes viruses (MHV) suggests a divergence time of 8 to 10 million years ago for HSV-1 and -2. Like MHV, HSV-1 and -2 cause local infections in their natural hosts, and direct contact between two individuals during the brief period of infectivity is needed for transmission. Because B virus, a nearer relative of HSV, depends on both oral and genital routes of transmission, we postulate that ancestral HSV (aHSV) was similar, and that for HSV-1 and -2 to diverge, genital and oral sites had to become microbiologically somewhat isolated from each other, while oral--oral and genital--genital contact had to be facilitated to maintain both aHSV strains. We propose that acquisition of continual sexual attractiveness by the ancestral human female and the adoption of close face-to-face mating, two hallmarks of human sexual behavior, provided the conditions for the divergence.