DYSERYTHROPOIESIS, POLYMYOPATHY, AND CARDIAC DISEASE IN 3 RELATED ENGLISH SPRINGER-SPANIELS
DYSERYTHROPOIESIS, POLYMYOPATHY, AND CARDIAC DISEASE IN 3 RELATED ENGLISH SPRINGER-SPANIELS
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DOI：
10.1111/j.1939-1676.1991.tb00942.x
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发表时间：
1991-05-01
影响因子：
2.6
通讯作者：
ALLAN, GS
中科院分区：
文献类型：
--
作者：
HOLLAND, CT;CANFIELD, PJ;ALLAN, GS
在三只相关的英国史宾格犬中观察到多系统疾病，这些犬从早期就表现出反流，缓慢进行性颞肌萎缩伴部分牙关紧闭，以及不太明显的全身骨骼肌萎缩。 所有犬均表现出中度红细胞生成不良性贫血、多肌病伴巨食道症和不同程度的心脏肥大。 患病率，病因，潜在的病理机制，和可能的遗传方式仍有待阐明。
A polysystemic disorder was observed in three related English Springer Spaniel dogs that demonstrated regurgitation from an early age, slowly progressive temporal muscle atrophy with partial trismus, and less pronounced generalized skeletal muscle atrophy. All dogs exhibited moderate dyserythropoietic anemia, polymyopathy with megaesophagus, and varying degrees of cardiomegaly. The prevalence, etiology, underlying pathomechanism, and possible mode of inheritance remain to be elucidated.