Alcohol Use Disorder and Comorbid Depression: A Randomized Controlled Trial Investigating the Effectiveness of Supportive Text Messages in Aiding Recovery
Alcohol Use Disorder and Comorbid Depression: A Randomized Controlled Trial Investigating the Effectiveness of Supportive Text Messages in Aiding Recovery
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DOI：
10.1093/alcalc/agz060
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发表时间：
2019-09-01
影响因子：
2.8
通讯作者：
Farren, Conor
中科院分区：
文献类型：
--
作者：
O'Reilly, Helen;Hagerty, Aisling;Farren, Conor
目的：这项随机对照试验的目的是研究在完成住院治疗计划后，在6个月的治疗期间，每日支持性短信对酒精使用障碍（AUD）和抑郁症双重诊断的个体的情绪和酒精消耗的影响。方法：95名患有AUD和共病抑郁症的成年参与者被招募到这个随机对照试验中，这些参与者在完成30天的康复计划后进行。干预组（n = 47）在6个月的时间里每天收到两次支持性短信，而对照组（n = 48）在6个月的时间里像往常一样接受治疗，两组治疗后都增加了6个月的随访。在基线、治疗3个月和6个月以及治疗后6个月随访时，测量前90天饮酒史以及抑郁、焦虑和压力症状。结果：治疗3个月时，干预组抑郁评分（P = 0.02）和应激感知评分（P < 0.01）明显低于中效组对照组。与中等效应的对照组相比，干预组从基线到6个月治疗点的单位日饮酒量也有显著更大的减少（P = 0.03）。在治疗后6个月的随访中，饮酒和情绪测量没有差异。结论：支持性短信在减轻抑郁和压力症状方面提供了早期的初步益处，在较长治疗期后对饮酒有进一步的积极影响。在干预结束后的六个月里，这种益处并没有持续下去。
Aim: The aim of this randomized controlled trial was to examine the impact of daily supportive text messages over a 6-month treatment period on mood and alcohol consumption in individuals with a dual diagnosis of alcohol use disorder (AUD) and depression following completion of an inpatient treatment programme.Method: Ninety-five adult participants with AUD and comorbid depression were recruited into this randomized control trial, which took place after completing a 30-day rehabilitation programme. The intervention group (n = 47) received twice-daily supportive text messages over 6-months while control participants (n = 48) had treatment as usual for a 6-month period, with an added 6-month post-treatment follow-up for both groups. Drinking history in the previous 90 days as well as symptoms of depression, anxiety and stress were measured at baseline, 3- and 6-month treatment points and 6-month post treatment follow up.Results: Depression scores (P = 0.02) and perceived stress scores (P < 0.01) were significantly reduced at 3-month treatment point in the intervention group relative to control participants with small to medium effect. The intervention group also showed a significantly greater reduction in units per drinking day from baseline to 6-month treatment point compared to the control group with a medium effect size (P = 0.03). There were no differences in drinking or mood measures at 6-month post treatment follow-up.Conclusions: Supportive text messages provide an early initial benefit in decreasing symptoms of depression and stress, with a further positive impact on alcohol consumption following a longer treatment period. Benefits did not persist six months after the intervention ended.