The effect of acquisition interval and spatial resolution on dynamic cardiac imaging with a stationary SPECT camera.
The effect of acquisition interval and spatial resolution on dynamic cardiac imaging with a stationary SPECT camera.
复制标题
采集间隔和空间分辨率对固定 SPECT 相机动态心脏成像的影响。
DOI：
10.1088/0031-9155/52/15/011
复制
发表时间：
2007
影响因子：
3.5
通讯作者：
Fu,Z
中科院分区：
文献类型：
--
作者：
Roberts,J;Maddula,R;Clackdoyle,R;DiBella,E;Fu,Z
The current SPECT scanning paradigm that acquires images by slow rotation of multiple detectors in body-contoured orbits around the patient is not suited to the rapid collection of tomographically complete data. During rapid image acquisition, mechanical and patient safety constraints limit the detector orbit to circular paths at increased distances from the patient, resulting in decreased spatial resolution. We consider a novel dynamic rotating slant-hole (DyRoSH) SPECT camera that can collect full tomographic data every 2 s, employing three stationary detectors mounted with slant-hole collimators that rotate at 30 rpm. Because the detectors are stationary, they can be placed much closer to the patient than is possible with conventional SPECT systems. We propose that the decoupling of the detector position from the mechanics of rapid image acquisition offers an additional degree of freedom which can be used to improve accuracy in measured kinetic parameter estimates. With simulations and list-mode reconstructions, we consider the effects of different acquisition intervals on dynamic cardiac imaging, comparing a conventional three detector SPECT system with the proposed DyRoSH SPECT system. Kinetic parameters of a two-compartment model of myocardial perfusion for technetium-99m-teboroxime were estimated. When compared to a conventional SPECT scanner for the same acquisition periods, the proposed DyRoSH system shows equivalent or reduced bias or standard deviation values for the kinetic parameter estimates. The DyRoSH camera with a 2 s acquisition period does not show any improvement compared to a DyRoSH camera with a 10 s acquisition period.
