Strain imaging of coronary arteries with intraluminal ultrasound: experiments on an inhomogeneous phantom.
Strain imaging of coronary arteries with intraluminal ultrasound: experiments on an inhomogeneous phantom.
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DOI：
10.1006/uimg.1996.0010
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发表时间：
1996
影响因子：
2.3
通讯作者：
B. Shapo;J. Crowe;R. Erkamp;S. Emelianov;M. J. Eberle;M. O’Donnell
中科院分区：
文献类型：
--
作者：
B. Shapo;J. Crowe;R. Erkamp;S. Emelianov;M. J. Eberle;M. O’Donnell
在冠状动脉中，了解动脉粥样硬化病变的相对硬度可以帮助医生选择最合适的治疗方式。由于软质材料比硬质材料支持更大的应变，因此该量的测量可以区分不同刚度的组织。在之前的论文中，我们描述了使用综合血管成形术和成像导管计算冠状动脉位移和应变的技术。在这里，我们证明了硬和软材料的组织模拟幻影可以区分与该设备。由于组织运动无法与导管运动先验区分开，我们在以气球几何中心为中心的坐标系中进行所有计算。该参考系仅取决于球囊形状，与导管运动无关。开发了一种专门的基于相关的相敏散斑跟踪算法来计算应变。最大幻影位移约为25微米，最大径向正常应变约为1.5%。
In coronary arteries, knowing the relative stiffness of atherosclerotic lesions can help physicians select the most appropriate therapeutic modality. Because soft material supports larger strains than hard, measurements of this quantity can distinguish tissue of differing stiffness. In a previous paper, we described techniques for computing displacements and strains in coronary arteries using an integrated angioplasty and imaging catheter. Here, we demonstrate that hard and soft materials in a tissue-mimicking phantom can be differentiated with this device. Because tissue motion cannot be distinguished from catheter motion a priori, we perform all computations in the coordinate system centered at the balloon's geometric center. This reference frame depends only on balloon shape and is independent of catheter motion. A specialized correlation-based, phase-sensitive speckle tracking algorithm has been developed to compute strain. Maximum phantom displacement was about 25 microns, and the maximum radial, normal strain was about 1.5 percent.