Chronic fatigue syndrome: aetiology, diagnosis and treatment.
Chronic fatigue syndrome: aetiology, diagnosis and treatment.
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DOI：
10.1186/1471-244x-9-s1-s1
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发表时间：
2009-10-23
期刊：
影响因子：
4.4
通讯作者：
Ramón Giménez JR
中科院分区：
文献类型：
--
作者：
Avellaneda Fernández A;Pérez Martín A;Izquierdo Martínez M;Arruti Bustillo M;Barbado Hernández FJ;de la Cruz Labrado J;Díaz-Delgado Peñas R;Gutiérrez Rivas E;Palacín Delgado C;Rivera Redondo J;Ramón Giménez JR
慢性疲劳综合征的特点是剧烈疲劳，持续时间超过6个月，并伴有其他相关症状。后者包括虚弱和容易引起的疲劳，这种疲劳在一夜睡眠后无法恢复。疲劳变得如此严重，迫使日常活动减少50%。由于其病因不明，尽管没有结论性的诊断测试，但人们考虑了不同的假设来解释这种疾病的起源（从免疫紊乱到创伤后氧化应激的存在）。通过排除引起疲劳的其他疾病来确定诊断。这种综合征在儿童和青少年中很少见，尽管疲劳症状本身在儿科患者中很常见。目前，尚无治疗慢性疲劳综合征的有效方法。这种综合征的治疗方法需要不同治疗方式的结合。慢性疲劳患者的症状特征要求教育、医疗和社会系统的快速适应，以防止现有系统产生的问题。由于影响这些患者的问题多种多样，需要多学科管理。这份文件是由罕见病研究所的一个跨学科工作组实现的，其目的是指出慢性疲劳综合征患者的主要社会和护理需求。为此，它不仅包括不同科学协会代表的观点，还包括患者协会的观点，因为他们知道他们的社会和卫生需求的真实历史。在跨学科的方法中，这项工作还回顾了慢性疲劳综合征的主要科学，医学，社会卫生和心理方面。
Chronic fatigue syndrome is characterised by intense fatigue, with duration of over six months and associated to other related symptoms. The latter include asthenia and easily induced tiredness that is not recovered after a night's sleep. The fatigue becomes so severe that it forces a 50% reduction in daily activities. Given its unknown aetiology, different hypotheses have been considered to explain the origin of the condition (from immunological disorders to the presence of post-traumatic oxidative stress), although there are no conclusive diagnostic tests. Diagnosis is established through the exclusion of other diseases causing fatigue. This syndrome is rare in childhood and adolescence, although the fatigue symptom per se is quite common in paediatric patients. Currently, no curative treatment exists for patients with chronic fatigue syndrome. The therapeutic approach to this syndrome requires a combination of different therapeutic modalities. The specific characteristics of the symptomatology of patients with chronic fatigue require a rapid adaptation of the educational, healthcare and social systems to prevent the problems derived from current systems. Such patients require multidisciplinary management due to the multiple and different issues affecting them. This document was realized by one of the Interdisciplinary Work Groups from the Institute for Rare Diseases, and its aim is to point out the main social and care needs for people affected with Chronic Fatigue Syndrome. For this, it includes not only the view of representatives for different scientific societies, but also the patient associations view, because they know the true history of their social and sanitary needs. In an interdisciplinary approach, this work also reviews the principal scientific, medical, socio-sanitary and psychological aspects of Chronic Fatigue Syndrome.