Three-dimensional EIT imaging of breast tissues: System design and clinical testing
Three-dimensional EIT imaging of breast tissues: System design and clinical testing
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DOI：
10.1109/tmi.2002.800602
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发表时间：
2002-06-01
影响因子：
10.6
通讯作者：
Meister, JD
中科院分区：
文献类型：
--
作者：
Cherepenin, VA;Karpov, AY;Meister, JD
描述了新的医学成像系统的开发和测试结果。该系统使用由256个电极组成的平面阵列，能够获得皮肤表面以下几厘米深区域的三维电导率分布图像。所开发的测量系统和图像重建算法可用于乳腺组织成像和诊断，特别是用于恶性肿瘤检测。给出了临床试验期间在体内获得的断层图像的例子。乳腺作为器官的靶子，随着月经周期、怀孕、哺乳和绝经后等生理事件的发生而在背景中发生变化。本研究的目的是评估电阻抗乳房摄影术在不同荷尔蒙状态的女性中研究乳腺状态的可能性。我们发现，不同组的电阻抗乳房X光照片在视觉上有明显的区别，在乳腺电导率方面也有统计学上的显著差异。我们关于不同生理时期乳腺电导率分布的数据将使我们能够在未来将其作为正常值，继续对不同病理类型的乳腺进行这一研究。
Results of development and testing of the new medical imaging system are described. The system uses a planar array consisting of 256 electrodes and enables obtaining images of the three-dimensional conductivity distribution in regions below the skin's surface up to several centimeters deep. The developed measuring system and image reconstruction algorithm can be used for breast tissue imaging and diagnostics, in particular for malignant tumor detection. Examples of tomographic images obtained in vivo during clinical tests are presented. The mammary gland, being an organ-target, alters at the background with such physiological events as menstrual cycle, pregnancy, lactation, and postmenopause. The objectives of this paper include estimation of the possibilities of electrical impedance mammography for investigation of mammary glands' state among women with different hormonal status. We found that electrical impedance mammograms from different groups had clear visual distinctions and statistically significant differences in mammary glands' conductivity. Our data on conductivity distribution in the mammary gland during different physiological periods will allow us to use it as normal values in the future, to continue this research on mammary glands with different pathology.