COLLAGEN HETEROGENEITY IN NORMAL HUMAN-BONE MARROW
COLLAGEN HETEROGENEITY IN NORMAL HUMAN-BONE MARROW
复制标题
DOI：
10.1111/j.1365-2141.1981.tb08462.x
复制
发表时间：
1981-01-01
影响因子：
6.5
通讯作者：
FOIDART, JM
中科院分区：
文献类型：
--
作者：
BENTLEY, SA;ALABASTER, O;FOIDART, JM
Paraffin embedded sections of formalin fixed, decalcified, normal, human vertebral bone were stained immunohistochemically for collagen types I, III and IV using the peroxidase-anti-peroxidase (PAP) technique. Preparations stained for collagen types I and III were virtually identical in appearance. These substrates were localized to the cytoplasm and fibrillar processes of a population of cells which were sparsely distributed within the hemopoietic compartment of the bone marrow, being particularly prominent in relation to the marrow sinusoids and fat spaces. They would appear to parallel the known distribution of reticulum cells, although their morphology differed in some respects from classical descriptions of the latter cell type. Type IV collagen was found in association with the endothelial lining of the sinusoids. Other connective tissue elements (bone, periosteum, endosteum, blood vessels, etc.) showed characteristic collagen heterogeneity. Collagen apparently is a significant component of the bone marrow connective tissue.
