The Prognostic Value of Preoperative Serum CEA and CA19-9 Values in Stage I-III Colorectal Cancer
The Prognostic Value of Preoperative Serum CEA and CA19-9 Values in Stage I-III Colorectal Cancer
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DOI:
10.5754/hge13599
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发表时间:
2014-06-01
影响因子:
--
通讯作者:
Xu, Ye
中科院分区:
文献类型:
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作者:
Wang, Ren-Jie;Song, Bao-Rong;Xu, Ye
Background/Aims: There is disagreement about the prognostic value of serum carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9) in patients who have stage I-III colorectal cancer. Therefore, we investigated the relationship between pre-operative serum CEA and CA19-9 levels and clinical outcome in patients with this disease. Methodology: The study included 724 patients who had received radical resection for stage I-III colorectal cancer in Fudan University Shanghai Cancer Center. We retrospectively investigated the relationship between patients' characteristics and survival, using univariate and multivariate analyses. In multivariate analysis, factors found significant in the univariate analysis were compared with patients' outcomes. Results: In univariate analysis, differentiation (P