Naps and circadian rhythms in postmenopausal women.

Naps and circadian rhythms in postmenopausal women.
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绝经后妇女的小睡和昼夜节律。

DOI:
10.1093/gerona/59.8.m844
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发表时间:
2004
期刊:
The journals of gerontology. Series A, Biological sciences and medical sciences
影响因子:
--
通讯作者:
Langer,RobertD
Langer,RobertD
中科院分区:
--
文献类型:
--
作者:
Yoon,In-Young;Kripke,DanielF;Elliott,JeffreyA;Langer,RobertD

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背景:对绝经后妇女的午睡模式以及午睡、昼夜节律和夜间睡眠之间的关系进行了评估。抑郁症妇女和健康志愿者的午睡和夜间睡眠进行了比较。方法:该研究包括436名年龄在50岁和81岁之间的绝经后妇女。使用DSM-IV轴I障碍的结构化临床访谈进行精神病学访谈。每个参与者都戴着一个手腕活动监测器,并在家里保持一周的每日睡眠日志。主要的尿褪黑激素代谢产物(6-硫酸酯基褪黑激素[aMT 6s])测定两个24小时内在home.Results.There没有显着差异,在午睡和夜间睡眠模式之间的抑郁症参与者(n= 30)和那些没有精神障碍的历史(n= 222)。午睡的时间出现了三个高峰:睡前1小时左右,醒来后8 - 9小时,醒来后2小时,按大小顺序排列。夜间小睡持续时间与唤醒时间和aMT 6s峰期之间存在显著的负相关。aMT 6s排泄的起始时间提前了32分钟,在evening nappers.Conclusions.Evening午睡,这些绝经后妇女的一个特点,可能与在这个年龄组的昼夜节律的推进。夜间小睡和早起之间的关系可能是先进的昼夜节律的一种常见表现,也可能是一种自我平衡效应。
Background.Napping patterns and relationships among naps, circadian rhythms, and nocturnal sleep were evaluated in postmenopausal women. Naps and nocturnal sleep were compared between depressed women and healthy volunteers.Methods.The study included 436 postmenopausal women between the ages of 50 and 81 years. Psychiatric interviews were conducted using the Structured Clinical Interview for DSM-IV Axis I Disorders. Each participant wore a wrist-activity monitor and kept a daily sleep log at home for 1 week. The major urinary melatonin metabolite (6-sulfatoxymelatonin [aMT6s]) was measured for two 24-hour periods at home.Results.There was no significant difference in naps and nocturnal sleep patterns between depressed participants (n= 30) and those with no history of mental disorder (n= 222). Three peaks occurred in the timing of napping: approximately 1 hour before bedtime, 8 to 9 hours after wake-up time, and 2 hours after waking, in descending order of magnitude. Significant inverse correlations were observed between evening nap duration and both wake-up time and aMT6s acrophase. The onset time of aMT6s excretion was advanced by 32 minutes in evening nappers.Conclusions.Evening napping, a characteristic of these postmenopausal women, may be related to an advance of circadian rhythms in this age group. Relationships between evening napping and earlier wake-up time may be a common manifestation of advanced circadian rhythms or may be a homeostatic effect.