How did we get here: what are droplets and aerosols and how far do they go? A historical perspective on the transmission of respiratory infectious diseases.
How did we get here: what are droplets and aerosols and how far do they go? A historical perspective on the transmission of respiratory infectious diseases.
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DOI：
10.1098/rsfs.2021.0049
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发表时间：
2021-12-06
期刊：
影响因子：
4.4
通讯作者：
Bourouiba L
中科院分区：
文献类型：
--
作者：
Randall K;Ewing ET;Marr LC;Jimenez JL;Bourouiba L
新冠肺炎疫情暴露了我们对病毒通过空气传播的理解存在重大差距。这些差距减缓了人们对疾病通过空气传播的认识，导致公共卫生政策混乱不堪，也阻碍了有关如何最好地减缓新冠肺炎传播的清晰信息。特别是，目前的建议基于四个原则：(1)呼吸道疾病的传播途径大多可以以“飞沫”和“气溶胶”的两种方式来看待；(2)这种二分法仅取决于飞沫的大小；(3)这些传播途径之间的截止尺寸是5微米；(4)每条传播途径的传播距离是有区别的。然而，这些断言之间的关系并没有得到当前科学知识的支持。在这里，我们重温这些概念的历史基础，以及它们是如何从19世纪到今天与科学和医学的各个领域之间复杂的相互作用而纠缠在一起的。这段回到过去的旅程突出了更好地合作和将科学成果融入实践的潜在解决方案，以建立一个具有更健全、更有远见和更有效的公共卫生政策的更具复原力的社会。
The COVID-19 pandemic has exposed major gaps in our understanding of the transmission of viruses through the air. These gaps slowed recognition of airborne transmission of the disease, contributed to muddled public health policies and impeded clear messaging on how best to slow transmission of COVID-19. In particular, current recommendations have been based on four tenets: (i) respiratory disease transmission routes can be viewed mostly in a binary manner of ‘droplets’ versus ‘aerosols’; (ii) this dichotomy depends on droplet size alone; (iii) the cut-off size between these routes of transmission is 5 µm; and (iv) there is a dichotomy in the distance at which transmission by each route is relevant. Yet, a relationship between these assertions is not supported by current scientific knowledge. Here, we revisit the historical foundation of these notions, and how they became entangled from the 1800s to today, with a complex interplay among various fields of science and medicine. This journey into the past highlights potential solutions for better collaboration and integration of scientific results into practice for building a more resilient society with more sound, far-sighted and effective public health policies.
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影响因子：
64.5
作者：
Hou, Yixuan J.;Okuda, Kenichi;Baric, Ralph S.
通讯作者：
Baric, Ralph S.
影响因子：
3.7
作者：
Bourouiba, Lydia;Dehandschoewercker, Eline;Bush, John W. M.
通讯作者：
Bush, John W. M.
DOI：
10.1001/jama.1918.26020410011008c
发表时间：
1918-07-01
影响因子：
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作者：
Doust, BC;Lyon, AB
通讯作者：
Lyon, AB
影响因子：
11.8
作者：
Guo, Zhen-Dong;Wang, Zhong-Yi;Chen, Wei
通讯作者：
Chen, Wei
影响因子：
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作者：
Glover, JA
通讯作者：
Glover, JA