Sex differences in the response to resistance exercise training in older people.
Sex differences in the response to resistance exercise training in older people.
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DOI：
10.14814/phy2.12834
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发表时间：
2016-06
影响因子：
2.5
通讯作者：
Gray SR
中科院分区：
文献类型：
--
作者：
Da Boit M;Sibson R;Meakin JR;Aspden RM;Thies F;Mangoni AA;Gray SR
抗阻运动训练被认为是有效的增加肌肉质量的老年人。蛋白质代谢数据的急性测量表明，反应的程度可能因性别而异。我们比较了一组老年（>65岁）男性和女性在18周抗阻运动训练后肌肉质量和功能的适应性反应。抗阻运动训练改善了膝伸肌最大扭矩、4 m步行时间、完成5次椅子起身的时间、肌肉解剖横截面积（阿克萨）和肌肉质量，对肌肉脂肪/水比或血糖、胰岛素、三酰甘油、IL-6和TNF-α无影响。膝伸肌最大扭矩和肌肉质量在性别间存在差异，男性比女性增加更多（P < 0.05）。女性最大扭矩增加了15.8 ± 10.6%，男性增加了41.7 ± 25.5%，而女性肌肉质量增加了8.8 ± 17.5%，男性增加了33.7 ± 25.6%。总之，这项研究表明，在适应的幅度，所采用的一些结果的措施，在18周的阻力运动训练的男性和女性之间的差异。这一现象背后的机制尚待建立。
Resistance exercise training is known to be effective in increasing muscle mass in older people. Acute measurement of protein metabolism data has indicated that the magnitude of response may differ between sexes. We compared adaptive responses in muscle mass and function to 18 weeks resistance exercise training in a cohort of older (>65 years) men and women. Resistance exercise training improved knee extensor maximal torque, 4 m walk time, time to complete five chair rises, muscle anatomical cross‐sectional area (ACSA) and muscle quality with no effect on muscle fat/water ratio or plasma glucose, insulin, triacylglycerol, IL‐6, and TNF‐α. Differences between sexes were observed for knee extensor maximal torque and muscle quality with greater increases observed in men versus women (P < 0.05). Maximal torque increased by 15.8 ± 10.6% in women and 41.7 ± 25.5% in men, whereas muscle quality increased by 8.8 ± 17.5% in women and by 33.7 ± 25.6% in men. In conclusion, this study has demonstrated a difference in the magnitude of adaptation, of some of the outcome measures employed, in response to 18 weeks of resistance exercise training between men and women. The mechanisms underlying this observation remain to be established.