Chiral recognition of organic molecules by atomic kinks on surfaces
Chiral recognition of organic molecules by atomic kinks on surfaces
复制标题
DOI：
10.1103/physrevlett.96.056103
复制
发表时间：
2006-02-10
影响因子：
8.6
通讯作者：
Hammer, B
中科院分区：
文献类型：
--
作者：
Greber, T;Sljivancanin, Z;Hammer, B
半胱氨酸在Au（17 11 9）（S）表面吸附后，出现两种不同的非镜像对称构象。这证明了手性杂识别，即，S扭结在邻位Au上的对映选择性（111）。角扫描X射线光电子衍射确定的结构同意从密度泛函理论计算。计算预测的吸附能约为2 eV，其中D-半胱氨酸结合140毫电子伏特强于L-半胱氨酸。经典的分子识别三点接触模型不能解释这些发现。
Two distinct non-mirror-symmetric conformations of D- and L-cysteine were found after adsorption on Au(17 11 9)(S). This demonstrates chiral heterorecognition, i.e., enantioselectivity of S kinks on vicinal Au(111). The structures as determined by angle scanned x-ray photoelectron diffraction agree well with those from density functional theory calculations. The calculations predict adsorption energies of approximate to 2 eV where D-cysteine binds 140 meV stronger than L-cysteine. The classical three point contact model for molecular recognition fails to explain these findings.