Endocrine Disruptors and Health Effects in Africa: A Call for Action.
Endocrine Disruptors and Health Effects in Africa: A Call for Action.
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非洲内分泌破坏者和健康影响：呼吁采取行动。
DOI：
10.1289/ehp1774
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发表时间：
2017-08-22
影响因子：
10.4
通讯作者：
Heindel JJ
中科院分区：
文献类型：
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作者：
Bornman MS;Aneck-Hahn NH;de Jager C;Wagenaar GM;Bouwman H;Barnhoorn IEJ;Patrick SM;Vandenberg LN;Kortenkamp A;Blumberg B;Kimmins S;Jegou B;Auger J;DiGangi J;Heindel JJ
非洲面临许多独特的环境挑战。不幸的是，它缺乏必要的基础设施来支持全面的环境研究，这些研究可以为环境政策提供科学基础。在非洲有许多已知的内分泌干扰物(EDCs)和其他危险化学品的来源。然而，尚未采取协调一致的办法来识别和监测这些污染物，并制定公共卫生干预战略。本评论总结了专家在第一届非洲内分泌干扰者会议上提出的科学证据。我们描述了一项“行动呼吁”，以利用现有的科学知识来解决EDC对非洲人类和野生动物健康的影响。我们确定了有关非洲新兴市场风险敞口的现有知识差距，并描述了如何需要精心设计的研究战略来填补这些差距。研究资源的缺乏和政策执行的滞后减缓了干预战略，并对促进非洲未来的健康构成了挑战。为了应对发展中国家带来的许多挑战，我们认为，非洲人应该带头优先考虑和评估环境危害，包括发展中国家。我们建议为化学品使用者制定教育和培训方案，采用预防原则，建立生物监测方案，并资助由非洲机构和私营公司领导和资助的基于社区的流行病学和野生动物研究方案。Https://doi.org/10.1289/EHP1774
Africa faces a number of unique environmental challenges. Unfortunately, it lacks the infrastructure needed to support the comprehensive environmental studies that could provide the scientific basis to inform environmental policies. There are a number of known sources of endocrine-disrupting chemicals (EDCs) and other hazardous chemicals in Africa. However, a coordinated approach to identify and monitor these contaminants and to develop strategies for public health interventions has not yet been made. This commentary summarizes the scientific evidence presented by experts at the First African Endocrine Disruptors meeting. We describe a “call to action” to utilize the available scientific knowledge to address the impact of EDCs on human and wildlife health in Africa. We identify existing knowledge gaps about exposures to EDCs in Africa and describe how well-designed research strategies are needed to address these gaps. A lack of resources for research and a lag in policy implementation slows down intervention strategies and poses a challenge to advancing future health in Africa. To address the many challenges posed by EDCs, we argue that Africans should take the lead in prioritization and evaluation of environmental hazards, including EDCs. We recommend the institution of education and training programs for chemical users, adoption of the precautionary principle, establishment of biomonitoring programs, and funding of community-based epidemiology and wildlife research programs led and funded by African institutes and private companies. https://doi.org/10.1289/EHP1774