CASE REPORT: Symptomatic Gastrointestinal Sarcoidosis: Case Report and Review of the Literature
CASE REPORT: Symptomatic Gastrointestinal Sarcoidosis: Case Report and Review of the Literature
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病例报告：症状性胃肠道结节病：病例报告和文献综述
DOI：
10.1023/a:1021711204498
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发表时间：
2004
影响因子：
3.1
通讯作者：
W. Cho
中科院分区：
文献类型：
--
作者：
R. S. Beniwal;O. Cummings;W. Cho
抗生素相关性腹泻（AAD）是抗生素治疗最常见的不良反应。我们的目的是确定酸奶膳食补充剂预防 AAD 的有效性。 202 名接受口服或静脉注射抗生素的住院患者被随机分配接受或不接受膳食酸奶补充剂（包含 227 克商业酸奶），并随访 8 天。研究组的平均年龄为 70 岁，其中 43% 为男性。依从性和 8 天随访率分别为 85% 和 91%。接受酸奶的患者腹泻频率较低（12% vs 24%；P = 0.04），腹泻总天数显着减少（23 vs 60）。接受和不接受酸奶的患者之间无腹泻患者的累积比例存在显着差异（P = 0.02）。总之，膳食补充酸奶是一种简单、有效且安全的治疗方法，可以降低 AAD 的发生率和持续时间。
Antibiotic-associated diarrhea (AAD) is the most common adverse effect of antibiotic therapy. Our aim was to determine the effectiveness of a dietary supplement of yogurt for prevention of AAD. Two hundred two hospitalized patients receiving oral or intravenous antibiotics were randomized to receive or not receive a dietary yogurt supplement, consisting of 227 grams of commercial yogurt, and followed for 8 days. Mean age of the study group was 70 years and 43% were male. Compliance and 8-day follow-up were 85% and 91%, respectively. Patients receiving yogurt reported less frequent diarrhea (12% vs 24%;P= 0.04), and significantly less total diarrheal days (23 vs 60). The cumulative proportions of patients without diarrhea were significantly different (P= 0.02) between patients receiving and not receiving yogurt. For conclusion, dietary supplementation with yogurt is a simple, effective, and safe treatment that decreases the incidence and duration of AAD.