Ligament structure, physiology and function.

Ligament structure, physiology and function.
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DOI:
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发表时间:
2004
影响因子:
1.9
通讯作者:
C. Frank
C. Frank
中科院分区:
医学4区
文献类型:
--
作者:
C. Frank

文献摘要

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韧带是一种特殊的结缔组织,具有非常有趣的生物力学特性。他们有能力适应每个人都需要执行的复杂功能。虽然韧带曾经被认为是惰性的,但它们实际上对影响其在生物体内功能的许多局部和全身因素有反应。韧带损伤导致其结构和生理学的急剧变化,并产生韧带功能通过疤痕组织的形成而恢复的情况,疤痕组织在生物学和生物力学上劣于它所替代的组织。本文将简要回顾正常与愈合的膝关节韧带的基本结构,生理和功能,特别是指什么是已知的两个最广泛的研究和临床相关的膝关节韧带,前交叉韧带(ACL)和内侧副韧带(MCL)的膝盖。那些读者希望更全面的信息来源韧带生物学和生物力学是指许多优秀的评论对这些主题。
Ligaments are specialized connective tissues with very interesting biomechanical properties. They have the ability to adapt to the complex functions that each are required to perform. While ligaments were once thought to be inert, they are in fact responsive to many local and systemic factors that influence their function within the organism. Injury to a ligament results in a drastic change in its structure and physiology and creates a situation where ligament function is restored by the formation of scar tissue that is biologically and biomechanically inferior to the tissue it replaces. This article will briefly review the basic structure, physiology and function of normal versus healing knee ligaments, referring specifically to what is known about two of the most extensively studied and clinically relevant knee ligaments, the anterior cruciate (ACL) and medial collateral (MCL) ligaments of the knee. Those readers wishing for more comprehensive sources of information on ligament biology and biomechanics are referred to many excellent reviews on these topics.