LIPID AND PHOSPHOLIPID FATTY-ACID COMPOSITION OF PLASMA, RED-BLOOD-CELLS, AND PLATELETS AND HOW THEY ARE AFFECTED BY DIETARY LIPIDS - A STUDY OF NORMAL SUBJECTS FROM ITALY, FINLAND, AND THE USA
LIPID AND PHOSPHOLIPID FATTY-ACID COMPOSITION OF PLASMA, RED-BLOOD-CELLS, AND PLATELETS AND HOW THEY ARE AFFECTED BY DIETARY LIPIDS - A STUDY OF NORMAL SUBJECTS FROM ITALY, FINLAND, AND THE USA
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DOI：
10.1093/ajcn/45.2.443
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发表时间：
1987-02-01
影响因子：
7.1
通讯作者：
IACONO, JM
中科院分区：
文献类型：
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作者：
DOUGHERTY, RM;GALLI, C;IACONO, JM
我们对来自三个国家农村地区的40-45岁男性进行了一项初步研究，以研究膳食脂肪对血浆、红细胞（rbc）和血小板的长期影响。血浆中胆固醇和磷脂水平存在差异。在这三个国家，红细胞和血小板的总磷脂相似。芬兰和意大利样本的红细胞中单个磷脂的模式与美国样本不同。在所有血浆和红细胞甘油磷脂中，意大利人的单不饱和脂肪酸含量最高，芬兰人的饱和脂肪酸含量最高；PUFAs在美国样品中含量最高。血小板的甘油磷脂也有类似的脂肪酸模式。我们得出结论，血浆、红细胞和血小板的甘油磷脂的脂肪酸组成反映了主要的膳食脂肪酸。
A pilot study was conducted to males 40-45 years old from rural areas of three countries to study the long-term effects of dietary fats on the lipids of plasma, red blood cells (RBCs), and platelets. Differences were observed in cholesterol and phospholipid levels of plasma. Total phospholipids of RBCs and platelets were similar in all three countries. The pattern of individual phospholipids of RBCs in the Finnish and Italian samples differed from the American samples. In all plasma and RBC glycerolphospholipids, the monounsaturated fatty acids were highest in the Italian and the saturated fatty acids were highest in the Finnish samples; PUFAs were highest in the USA samples. Platelet glycerolphospholipids followed similar fatty acid patterns. We concluded that the fatty acid compositions of the glycerolphospholipids of plasma, RBCs, and platelets reflect the major dietary fatty acids.