Reduction in the incidence of invasive listeriosis in Foodborne Diseases Active Surveillance Network sites, 1996-2003
Reduction in the incidence of invasive listeriosis in Foodborne Diseases Active Surveillance Network sites, 1996-2003
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DOI：
10.1086/511006
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发表时间：
2007-02-15
影响因子：
11.8
通讯作者：
Griffin, Patricia M.
中科院分区：
文献类型：
--
作者：
Voetsch, Andrew C.;Angulo, Frederick J.;Griffin, Patricia M.
背景。李斯特菌病是美国食源性疾病患者死亡的主要原因。监测发病率是李斯特菌病监测和控制的重要内容。方法。从 1996 年到 2003 年，我们对从食源性疾病主动监测网络中所有临床诊断实验室的正常无菌场所获得的单核细胞增生李斯特氏菌分离株进行了基于人群的监测。结果。从 1996 年到 2003 年，实验室确诊的侵袭性李斯特菌病的发病率下降了 24%；妊娠相关疾病减少了 37%，而 50 岁以上患者则减少了 23%。 1997 年至 2001 年间，西班牙裔人群的发病率最高。不同年龄组和种族的发病率差异可能是通过饮食偏好来解释的。结论。李斯特菌病发病率的显着下降可能与自 1996 年以来即食食品中单核细胞增生李斯特氏菌污染的流行率下降有关。2003 年的粗发病率为每 100 万人口 3.1 例，接近政府的健康人口目标，即到 2005 年每 100 万人口 2.5 例。李斯特菌病发病率的进一步下降需要行业和政府继续努力减少食品污染，并继续努力进行教育 消费者和临床医生。
Background. Listeriosis is a leading cause of death among patients with foodborne diseases in the United States. Monitoring disease incidence is an important element of listeriosis surveillance and control.Method. We conducted population-based surveillance for Listeria monocytogenes isolates obtained from normally sterile sites at all clinical diagnostic laboratories in the Foodborne Diseases Active Surveillance Network from 1996 through 2003.Results. The incidence of laboratory-confirmed invasive listeriosis decreased by 24% from 1996 through 2003; pregnancy-associated disease decreased by 37%, compared with a decrease of 23% for patients >= 50 years old. The highest incidence was reported among Hispanic persons from 1997 through 2001. Differences in incidence by age group and ethnicity may be explained by dietary preferences.Conclusion. The marked decrease in the incidence of listeriosis may be related to the decrease in the prevalence of L. monocytogenes contamination of ready-to-eat foods since 1996. The crude incidence in 2003 of 3.1 cases per 1 million population approaches the government's Healthy People objective of 2.5 cases per 1 million population by 2005. Further decreases in listeriosis incidence will require continued efforts of industry and government to reduce contamination of food and continued efforts to educate consumers and clinicians.