Extracellular calcium and magnesium in preeclampsia and eclampsia.
Extracellular calcium and magnesium in preeclampsia and eclampsia.
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DOI：
10.2307/25549719
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发表时间：
2007-08-01
影响因子：
1
通讯作者：
Momoh, S M
中科院分区：
文献类型：
--
作者：
Idogun, E S;Imarengiaye, C O;Momoh, S M
先兆子痫的原因仍然未知，钙和镁的补充被建议作为预防手段。本研究的目的是评估镁和钙的血浆和脑脊液中的尼日利亚妇女先兆子痫和子痫。背景是尼日利亚的贝宁大学教学医院。这是一项横断面研究，包括11名患者和23名对照。计算平均值、标准差和平均值的标准误差（SEM）。采用t检验法。患者的血浆钙显著低于对照组（9.2 +/- 1.02 Vs 9.98 +/-0.87 mg/dl，P 0.043）“t”检验。患者的CSF钙和镁水平低于对照组（5.66 +/- 1.22 vs 6.67 +/- 1.15 mg/ dl，P 0.043和1.75 +/- 0.56 vs 1.91 +/- 0.19 mg/dl，P 0.001）。< 0.0001）。子痫前期和子痫患者存在细胞外钙镁减少。这种减少可能与这些疾病有因果关系。
The cause of preeclampsia remains unknown and calcium and magnesium supplement are being suggested as means of prevention. The objective of this study was to assess magnesium and calcium in the plasma and cerebrospinal fluid of Nigerian women with preeclampsia and eclampsia. Setting was University of Benin Teaching Hospital, in Nigeria. It was a cross-sectional study comprising of eleven patients and twenty-three controls. The mean, standard deviation and Standard Error of Mean (SEM) were calculated. Student 't' test method was applied. Plasma calcium was significantly lower in patients than controls (9.2 +/- 1.02 Vs 9.98 +/- 0.87mg/dl, P 0.043) "t" test. The CSF calcium and magnesium levels were lower in patients than controls, (5.66 +/- 1.22 vs 6.67 +/- 1.15 mg/ dl, P 0.043 and 1.75 +/- 0.56 vs 1.91 +/- 0.19 mg/dl, P 0. < 0.0001) respectively. There is extracellular calcium and magnesium reduction in patients with preeclampsia and eclampsia. This reduction may have a cause and effect relationship with these disorders.