The Drosophila cytokine, GBP: A model that illuminates the yin-yang of inflammation and longevity in humans?

The Drosophila cytokine, GBP: A model that illuminates the yin-yang of inflammation and longevity in humans?
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DOI:
10.1016/j.cyto.2018.02.016
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发表时间:
2018-10
期刊:
影响因子:
3.8
通讯作者:
Hayakawa Y
Hayakawa Y
中科院分区:
医学3区
文献类型:
--
作者:
Shears SB;Hayakawa Y

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Our laboratories have determined that the Drosophila cytokine, Growth-blocking peptide (GBP), mediates its biological effects through the Mthl10 G-protein coupled receptor. In this Cytokine Stimulus, we discuss the functional plasticity of the GBP/Mthl10 axis, and we propose that conserved components of this regulatory network may be relevant to human health.
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