Porous fluorine-doped tin oxide as a promising substrate for electrochemical biosensors-demonstration in hydrogen peroxide sensing
Porous fluorine-doped tin oxide as a promising substrate for electrochemical biosensors-demonstration in hydrogen peroxide sensing
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多孔掺氟氧化锡作为电化学生物传感器的理想基底--过氧化氢传感演示
DOI：
10.1039/c4tb01191k
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发表时间：
2014-01-01
影响因子：
7
通讯作者：
Lu, Shih-Yuan
中科院分区：
文献类型：
--
作者：
Lee, Kuan-Ting;Liu, Dai-Min;Lu, Shih-Yuan
高亲水性的导电多孔基底在电化学生物传感器中作为主体电极是有利的，不仅提供快速的电荷传输和大的感测表面积，而且还提供在水性分析物中的必要的润湿性。在这项研究中，廉价，高亲水性（接触角< 5度），导电（方块电阻为17 Ω矩形（-1））多孔氟掺杂氧化锡（FTO）玻璃是由商业FTO玻璃与一种新的，简单的，一步Sn 4+为基础的阳极处理过程，并作为主电极的电化学生物传感器。我们证明了它的上级性能与过氧化氢传感。过氧化氢传感器是通过简单地沉积铂纳米粒子到多孔FTO基板（PFTO）的表面与多元醇的过程。还研究了Pt修饰的商业FTO（CFTO）作为对照。与Pt修饰的PFTO实现的灵敏度几乎是一个数量级高于Pt修饰的CFTO（25.8 vs. 2.69 mA M-1），和响应时间从36秒的Pt修饰的CFTO缩短到1秒的Pt修饰的PFTO。PFTO被证明是电化学生物传感器中主体功能材料的有前途的电极基底，并且可以容易地应用于各种生物物质的传感。
Conducting porous substrates of high hydrophilicity are advantageous in applications of electrochemical biosensors as host electrodes, offering not only fast charge transport and large sensing surface areas but also necessary wettability in aqueous analytes. In this study, inexpensive, highly hydrophilic (contact angle < 5 degrees), conducting (sheet resistance of 17 Omega rectangle(-1)) porous fluorine-doped tin oxide (FTO) glass is fabricated from commercial FTO glass with a novel, simple, one-step Sn4+-based anodic treatment process, and used as a host electrode for electrochemical biosensors. We demonstrate its superior performance with hydrogen peroxide sensing. The hydrogen peroxide sensor is fabricated by simply depositing Pt nanoparticles onto the surface of the porous FTO substrate (PFTO) with a polyol process. Pt-decorated commercial FTO (CFTO) is also investigated as a control. The sensitivity achieved with the Pt-decorated PFTO is almost one order of magnitude higher than that of the Pt-decorated CFTO (25.8 vs. 2.69 mA M-1), and the response time is shortened from 36 s for the Pt-decorated CFTO to 1 s for the Pt-decorated PFTO. The PFTO proves to be a promising electrode substrate for host functional materials in electrochemical biosensors and can be readily applied to sensing of a wide variety of biosubstances.