Calcium Chloride Infusions are Not Associated with Improved Outcomes in Neonates Undergoing Cardiac Operations.
Calcium Chloride Infusions are Not Associated with Improved Outcomes in Neonates Undergoing Cardiac Operations.
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氯化钙输注与正在进行心脏手术的新生儿的预后无关。
DOI：
10.1007/s00246-021-02730-x
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发表时间：
2022-03
影响因子：
1.6
通讯作者：
中科院分区：
文献类型：
--
作者：
新生儿心脏的性能取决于钙输送到心肌，这对接受心脏手术的新生儿的使用和影响很少。通过支持该患者人群的心脏输出。包括2015年6月1日至12/31/2018的心脏手术分为两组：那些接受术后氯化钙输注的人（钙组）和没有的人（对照组）。在手术后的前24小时内，最大血管活性肌力评分（VIS）> 15接受术后钙输注和69例患者，手术时的体重，手术复杂性，心肺旁路时间相似38例（55％）不接受钙输注（p = 0.08）。在开始的24个小时内，接受了心脏手术的新生儿的LOS或组之间的操作死亡率。
Neonatal cardiac performance is dependent on calcium delivery to the myocardium. Little is known about the use and impact of calcium chloride infusions in neonates who undergo cardiac surgery. We hypothesized that the use of calcium chloride infusions would decrease the doses required of traditional inotropic and vasoactive medications by supporting cardiac output in this patient population. We performed a single-institution, retrospective, cohort study. All neonates (≤ 30 days old) undergoing cardiac surgery from 06/01/2015 through 12/31/2018 were included. Patients were divided into two groups: those who received postoperative calcium chloride infusions (calcium group) and those who did not (control group). The primary outcome was the occurrence of a maximum Vasoactive Inotropic Score (VIS) > 15 in the first 24 h following surgery. One hundred and thirty-five patients met inclusion criteria. Sixty-six patients received postoperative calcium infusions and 69 patients did not. Gestational age, weight at surgery, age at surgery, surgical complexity and cardiopulmonary bypass times were similar between groups. Forty-two (70%) patients receiving calcium had a postoperative maximum VIS > 15 compared with 38 (55%) patients not on a calcium infusion (p = 0.08). There were no differences in postoperative length of ventilation, time to enteral feeding, hospital LOS, or operative mortality between groups. Calcium chloride infusions in neonates who underwent cardiac surgery did not decrease exposure to other inotropic and vasoactive agents in the first 24 post-operative hours or improve patient outcomes.
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影响因子：
4.1
作者：
Gaies, Michael G.;Gurney, James G.;Hirsch, Jennifer C.
通讯作者：
Hirsch, Jennifer C.
影响因子：
24
作者：
Graham, Eric M.;Martin, Renee H.;Atz, Andrew M.
通讯作者：
Atz, Andrew M.
DOI：
10.1016/j.jtcvs.2013.03.013
发表时间：
2014-01-01
影响因子：
6
作者：
Butts, Ryan J.;Scheurer, Mark A.;Graham, Eric M.
通讯作者：
Graham, Eric M.
影响因子：
6
作者：
Charpie, JR;Dekeon, MK;Kulik, TJ
通讯作者：
Kulik, TJ
影响因子：
5
作者：
Balaguru, D;Haddock, PS;Artman, M
通讯作者：
Artman, M