Intracellular inducer Hg2+ concentration is rate determining for the expression of the mercury-resistance operon in cells.
Intracellular inducer Hg2+ concentration is rate determining for the expression of the mercury-resistance operon in cells.
复制标题
细胞内诱导剂 Hg2 浓度是细胞中耐汞操纵子表达的速率决定因素。
DOI：
10.1128/jb.178.9.2712-2714.1996
复制
发表时间：
1996
影响因子：
3.2
通讯作者：
Misra,TK
中科院分区：
文献类型：
--
作者：
Yu,H;Chu,L;Misra,TK
Experiments involving mercury resistance mer operon-lacZ fusions, point mutations in the mercuric ion reductase merA gene, and transcomplementation have revealed that in Hg2+-resistant cells, the inducer Hg2+ concentration is rate determining for activation of transcription. mer operon expression is activated by the presence of nanomolar concentrations of Hg2+ in liquid media only when the mercuric ion reductase function is artificially inactivated in cells, whereas cells with active mercuric ion reductase require micromolar concentrations of Hg2+ for effective induction of the operon.
