Genetic oscillation patterns

Genetic oscillation patterns
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遗传振荡模式

DOI:
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发表时间:
2009
期刊:
影响因子:
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通讯作者:
Sandeep Krishna
Sandeep Krishna
中科院分区:
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文献类型:
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作者:
M. Jensen;S. Pigolotti;Sandeep Krishna

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摘要 我们应用符号动力学来分析从细胞基因调控中获得的动态测量结果。例如,将蛋白质浓度的时间信号划分为单调增加或降低水平的区域,给出了一种自然的符号划分,可用于猜测潜在的负反馈环路。我们进一步研究了如何在六角晶格上放置负反馈环,并研究了其动力学后果。
Abstract We apply symbolic dynamics to analyze dynamical measurements obtained from gene regulations of cells. Dividing the temporal signals of for instance protein concentrations into regimes of monotonic increasing or decreasing levels gives a natural symbolic division which can be applied to guess the underlying negative feed-back loops. We further study how negative feed-back loops can be placed on a hexagonal lattice and investigate the dynamical consequences of that.
DOI: 10.1126/science.281.5382.1519
发表时间: 1998-09-04
期刊: SCIENCE
影响因子: 56.9
作者:
Ishiura, M;Kutsuna, S;Kondo, T
通讯作者: Kondo, T