Organization and development of direction-selective circuits in the retina.
Organization and development of direction-selective circuits in the retina.
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DOI：
10.1016/j.tins.2011.08.002
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发表时间：
2011-12
影响因子：
15.9
通讯作者：
Feller MB
中科院分区：
文献类型：
--
作者：
Wei W;Feller MB
The direction selective circuit in the retina extracts the directional information of image motion in the visual scene. It is a classic model for neural circuit analysis because its input and output are well-defined and accessible to physiological measurements. However, the neural basis of direction selectivity is still not fully understood. Indeed, this ostensibly simple computation arises from a collection of complex neural mechanisms at all levels of circuit organization. In this review, we describe recent advances in genetic, imaging and optogenetic techniques that have improved our understanding of the synaptic organization and development underlying retinal direction selectivity.
