INCREASED C-FOS EXPRESSION IN NUCLEUS OF THE SOLITARY TRACT CORRELATED WITH CONDITIONED TASTE-AVERSION TO SUCROSE IN RATS
INCREASED C-FOS EXPRESSION IN NUCLEUS OF THE SOLITARY TRACT CORRELATED WITH CONDITIONED TASTE-AVERSION TO SUCROSE IN RATS
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DOI：
10.1016/0304-3940(94)90648-3
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发表时间：
1994-05-19
影响因子：
2.5
通讯作者：
SMITH, GP
中科院分区：
文献类型：
--
作者：
HOUPT, TA;PHILOPENA, JM;SMITH, GP
用c-Fos样免疫反应性（c-FLI）技术研究了大鼠条件性味觉厌恶（CTA）形成前后孤束核（NTS）神经元对标准味觉刺激的反应模式。虽然非条件性口服输注蔗糖溶液不会诱导NTS中的c-FLI，但在三次蔗糖与氯化锂注射配对后，蔗糖在口服输注后1小时诱导中间NTS中的c-FLI。通过反复输注单独的蔗糖使CTA消失逆转了c-FLI的诱导。
The pattern of neuronal activation in the rat nucleus of the solitary tract (NTS) in response to a standard gustatory stimulus was examined using c-Fos-like immunoreactivity (c-FLI) before and after conditioned taste aversion (CTA) formation. While unconditioned oral infusions of sucrose solution did not induce c-FLI in the NTS, after three pairings of sucrose with lithium chloride injections, sucrose induced c-FLI in the medial intermediate NTS 1 h after oral infusion. Extinction of the CTA by repeated infusions of sucrose alone reversed the induction of c-FLI.