The impact of cognitive impairment on perceived workforce performance: Results from the International Mood Disorders Collaborative Project
The impact of cognitive impairment on perceived workforce performance: Results from the International Mood Disorders Collaborative Project
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DOI：
10.1016/j.comppsych.2014.08.051
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发表时间：
2015-01-01
影响因子：
7.3
通讯作者：
Kennedy, Sidney H.
中科院分区：
文献类型：
--
作者：
McIntyre, Roger S.;Soczynska, Joanna Z.;Kennedy, Sidney H.
背景：认知功能障碍和抑郁严重程度是成人重度抑郁症（MDD）患者职场适应的关键中介因素。在此，我们试图确定抑郁严重程度和认知功能障碍的测量与感知的整体残疾、工作场所表现和生活质量的关联程度。方法：对2008年1月至2013年7月参加国际情绪障碍合作项目（IMDCP）的260名被诊断为dsm - iv - tr定义的重度抑郁症的参与者的数据进行事后分析。采用了工作功能、整体残疾、抑郁严重程度、认知功能和生活质量的测量方法。采用多元线性回归方程对数据进行分析。结果：感知的整体失能显著地被抑郁严重程度的临床评分（beta = 0.54）和感知的注意力不集中（beta = 0.24）预测，占方差的37%。此外，感知注意力不集中（beta = 0.58）和抑郁严重程度的临床评级（beta = 0.18）也是感知工作效率/绩效的重要预测因素，占方差的38%。最后，抑郁严重程度的临床评分（beta = -0.54）和感知注意力不集中（beta = -0.18）是感知生活质量的显著负向预测因子，占方差的34%。结论：本文分析的主要发现是，认知功能障碍的主观测量在更大程度上解释了工作场所绩效的可变性，而不是总体抑郁症状的严重程度。相反，与认知测量相比，总体抑郁症状严重程度在全球残疾测量中占更大程度的可变性。成人重度抑郁症的治疗策略应该解决认知功能障碍的问题，以提高工作参与度和表现。(C) 2014爱思唯尔公司版权所有。
Background: Cognitive dysfunction and depression severity are key mediators of workplace adjustment in adults with major depressive disorder (MDD). Herein, we sought to determine the extent to which measures of depression severity and cognitive dysfunction were associated with perceived global disability, workplace performance and quality of life.Method: A post hoc analysis was conducted using data from 260 participants with a diagnosis of DSM-IV-TR-defined MDD who were enrolled in the International Mood Disorders Collaborative Project (IMDCP) between January 2008 and July 2013. Measures of workplace function, global disability, depression severity, cognitive function, and quality of life were employed. These data were analyzed using a multiple variable linear regression equations.Results: Perceived global disability was significantly predicted by clinical ratings of depression severity (beta = 0.54), and perceived inattention (beta = 0.24), accounting for 37% of the variance. In addition, perceived inattention (beta = 0.58) and clinical ratings of depression severity (beta = 0.18), were also significant predictors of perceived workplace productivity/performance, accounting for 38% of the variance. Finally, both clinical ratings of depression severity (beta = -0.54), and perceived inattention (beta = -0.18) were significant inverse predictors of perceived quality of life, accounting for 34% of the variance.Conclusion: The overarching finding in the analysis herein is that workplace performance variability is explained by subjective measures of cognitive dysfunction to a greater extent than total depression symptom severity. Conversely, total depression symptom severity accounts for a greater degree of variability in global measures of disability relative to cognitive measures. Treatment strategies for adults with major depressive disorder should address issues of cognitive dysfunction to improve workforce participation and performance. (C) 2014 Elsevier Inc. All rights reserved.