Comparison of antibacterial activity of Ciprofloxacin and Cephalexin against some common bacterial species isolates from donkey wounds around the vicinity of Tando j am Sindh Pakistan.
Comparison of antibacterial activity of Ciprofloxacin and Cephalexin against some common bacterial species isolates from donkey wounds around the vicinity of Tando j am Sindh Pakistan.
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DOI：
10.19045/bspab.2021.100114
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发表时间：
2021-01-01
影响因子：
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通讯作者：
Ujjan, Imtiaz Ali
中科院分区：
文献类型：
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作者：
Arbab, Safia;Buriro, Rehana Shahnawaz;Ujjan, Imtiaz Ali
在目前的研究中获得的结果增加了对Tandoj am Sindh Pakistan附近的马皮肤伤口细菌感染的了解，并与两种不同的抗生素（环丙沙星和头孢氨苄）对一些常见的病原体进行了比较。在该实验期间，从驴伤口收集总共50个伤口样品。将样本放入冷链中。50份样品均检出金黄色葡萄球菌（45%）、大肠埃希菌（35%）、志贺氏菌（33%）和沙门氏菌（25%）等致病菌。对分离的细菌进行头孢氨苄和环丙沙星的药敏试验。S.金黄色葡萄球菌（18 mm）对头孢氨苄（18 mm）的敏感性最高，其次是大肠埃希菌（15 mm）、志贺氏菌（13 mm）和沙门氏菌（13 mm）。(13 mm）。而环丙沙星对沙门氏菌有较强的抗菌活性。aureus（2 4mm）、E.大肠杆菌（20 mm）、志贺氏菌（15 mm）和沙门氏菌属（Salmonella spp.）(18 mm）。本研究结果显示，抗生素环丙沙星和头孢氨苄对分离的微生物均表现出较高的敏感性。金黄色葡萄球菌对头孢氨苄的敏感性较高，其次为大肠埃希菌、志贺氏菌和沙门氏菌.环丙沙星对金黄色葡萄球菌和大肠杆菌有较强的抗菌活性。大肠杆菌最低，志贺氏菌和沙门氏菌最低。
The results obtained in the current study have increased knowledge on bacterial infections of skin wounds in equines around the vicinity of Tandoj am Sindh Pakistan and compare with two different antibiotics (Ciprofloxacin and Cephalexin) against some common p athogens. During this experiments, a total of 50 wound samples were collected from donkey wounds. Specimens were brought in a cold chain . All 50 samples were fou nd contaminated with differen t bacterial organisms including Staphalococcus aureus (45%), Escherichia coli (35%), Shigella (33%) and Salmonella spp (25%) . The isolated bacterial organisms were checked f or their susceptibility against Cephalexin and Cipr ofloxacin . S. aureus (18 mm), showed higher sensitivity against Cephalexin (18 mm) and followed by E scherichia coli, (15 mm), Shigella (13 mm), and Salmonella spp. (13 mm) respectively. Whereas Ciprofloxacin showed more significant activity against S. aureus (2 4 mm), E. coli (20 mm), Shigella (15 mm), and Salmonella spp. (18 mm). The results of this study revealed that both antibiotics Ciprofloxacin and Cephalexin showed higher sensitivity against the isolated microorganisms. S.aureus showed greater susceptibility ag ainst Cephalexin, followed by Escherichia coli, Shigella, and Salmonella spp. In contrast, Ciprofloxacin showed higher activity against Staphylococcus aureus and E . coli, and minimum for Shigella and Salmonella spp.