Dual activation in a homolytic coupling reaction promoted by an enantioselective dinuclear vanadium(IV) catalyst
Dual activation in a homolytic coupling reaction promoted by an enantioselective dinuclear vanadium(IV) catalyst
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DOI：
10.1016/j.tetlet.2004.01.007
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发表时间：
2004-02-23
影响因子：
1.8
通讯作者：
Sasai, H
中科院分区：
文献类型：
--
作者：
Somei, H;Asano, Y;Sasai, H
提出了2-萘酚衍生物均解偶联反应中双活化催化的新概念。双核钒(IV)催化剂(R，S，S)-1a促进了2-萘酚衍生物的氧化偶联反应，具有较高的反应活性和对映选择性。(R，S，S)-1a促进的2-萘酚氧化偶联反应速度是单核配合物(S)-3的48倍，催化剂负载量越低，对映体选择性和化学产率越高，这一双重活化机理得到了支持。(C)2004爱思唯尔有限公司。保留所有权利。
A new concept of dual activation catalysis in homolytic coupling reaction of 2-naphthol derivatives is described. The dinuclear vanadium(IV) catalyst (R,S,S)-1a promotes the oxidative coupling reaction of 2-naphthol derivatives with high reactivity and enantioselectivity. This dual activation mechanism is supported by the fact that the reaction rate of oxidative coupling of 2-naphthol promoted by the (R,S,S)-1a is 48 times faster than that of the mononuclear complex (S)-3 and a lower catalyst loading of (R,S,S)-1a shows higher catalyst efficiency both in enantioselectivity and chemical yield. (C) 2004 Elsevier Ltd. All rights reserved.