Photoredox Catalytic Phosphine-Mediated Deoxygenation of Hydroxylamines Enables the Construction of N-Acyliminophosphoranes
Photoredox Catalytic Phosphine-Mediated Deoxygenation of Hydroxylamines Enables the Construction of N-Acyliminophosphoranes
复制标题
光氧化还原催化膦介导的羟胺脱氧能够构建 N-酰基亚氨基正膦
DOI：
10.1021/acs.orglett.2c02226
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发表时间：
2022
期刊：
影响因子：
5.2
通讯作者：
Jiannan Zhao
中科院分区：
文献类型：
--
作者：
Wencheng Han;Junqi Su;Jia-Nan Mo;Jiannan Zhao
磷酰基自由基化学近年来受到越来越多的关注。在这里，我们报告的生成酰胺基自由基通过光催化脱氧羟胺与三苯基膦。这种方法提供了一种新的和方便的路线，以不同的范围ofN-酰基亚胺膦在中等到良好的产率在可见光光光氧化还原条件下。荧光猝灭实验表明，激发态的有机光催化剂（4CzIPN）被氧化猝灭的Cu（II）盐。
The chemistry of phosphoranyl radicals has received increasing attention in recent years. Here, we report the generation of amidyl radicals through photocatalytic deoxygenation of hydroxylamines with triphenylphosphine. This methodology offers a novel and convenient route to a diverse range ofN-acyliminophosphoranes in moderate to good yields under visible-light photoredox conditions. Fluorescence quenching experiments suggest that the excited-state of the organic photocatalyst (4CzIPN) was oxidatively quenched by a Cu(II) salt.