Highly enantioselective addition of ketones to nitroolefins catalyzed by new thiourea-amine bifunctional organocatalysts.
Highly enantioselective addition of ketones to nitroolefins catalyzed by new thiourea-amine bifunctional organocatalysts.
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DOI：
10.1039/b517937h
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发表时间：
2006-03
影响因子：
4.9
通讯作者：
S. Tsogoeva;Shengwei Wei
中科院分区：
文献类型：
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作者：
S. Tsogoeva;Shengwei Wei
本文报道了一种新的有效的有机催化体系：伯胺衍生的手性硫脲催化剂和AcOH-H_2 O添加剂，该体系可将不同的酮以高产率（82-99%）和对映选择性（90-99%）转化为γ-硝基酮。
A new and effective organocatalytic system: primary amine derived chiral thiourea catalyst and AcOH-H2O additive, which converts different ketones to gamma-nitroketones in high yields (82-99%) and enantioselectivities (90-99%) has been described.