Binding sites for transcription factor SF-1 in promoter regions of genes encoding mouse steroidogenesis enzymes 3βHSDI and P450c17

Binding sites for transcription factor SF-1 in promoter regions of genes encoding mouse steroidogenesis enzymes 3βHSDI and P450c17
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DOI:
10.1007/s10541-005-0239-4
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发表时间:
2005-10-01
影响因子:
2.8
通讯作者:
Osadchuk, AV
Osadchuk, AV
中科院分区:
生物学4区
文献类型:
--
作者:
Busygina, TV;Vasiliev, GV;Osadchuk, AV

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利用DNA样品的凝胶阻滞和特异性抗体,在小鼠Cyp17基因启动子区域的-53/-44和-285/-270位置以及小鼠3 β HSDI基因启动子区域的-117/-108位置发现了转录因子SF-1的结合位点。
Using gel retardation of DNA samples and specific antibodies, binding sites for the transcription factor SF-1 were found in positions -53/-44 and -285/-270 in the promoter region of the mouse Cyp17 gene and in position -117/-108 of the promoter region of the mouse 3 beta HSDI gene.