Long-term psychological distress in women at risk for hereditary breast cancer adhering to regular surveillance: a risk profile
Long-term psychological distress in women at risk for hereditary breast cancer adhering to regular surveillance: a risk profile
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DOI：
10.1002/pon.3039
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发表时间：
2013-03-01
期刊：
影响因子：
3.6
通讯作者：
Tibben, Aad
中科院分区：
文献类型：
--
作者：
den Heijer, Mariska;Seynaeve, Caroline;Tibben, Aad
背景：一些有遗传性乳腺癌风险的妇女心理困扰的风险增加。为了为个别妇女提供量身定制的支助，有必要提供一种工具，使其能够在早期阶段识别心理上脆弱的妇女。本研究的目的是：(1)探索坚持定期监测的有遗传性乳腺癌风险的女性的长期心理困扰，(2)根据多因素风险概况确定易受长期心理困扰的女性。方法：对197名坚持乳腺癌监测的高危妇女进行基线（T0）和5-8年后（T1）的一般焦虑和癌症相关焦虑评估。在T0时评估的应对方式、原系家庭中乳腺癌的发生、乳腺癌风险认知和乳房自我检查的频率作为长期痛苦的预测变量（T1）进行了检查。结果：随着时间的推移，女性报告的干扰和回避显著减少。在因乳腺癌失去一级亲属的女性中，入侵水平增加。长期痛苦增加的预测因素是被动和姑息性应对方式、过度的乳房自我检查和高估乳腺癌风险。另一方面，通过培养让人安心的想法来应对，预示着长期痛苦的减少。结论：在确定风险概况的基础上，有可能在早期阶段确定弱势妇女，然后可能向她们提供额外的和量身定制的支持。版权所有：John Wiley & Sons， Ltd
Background: Some women at risk for hereditary breast cancer are at increased risk of psychological distress. In order to tailor support for individual women, the availability of a tool enabling the identification of psychologically vulnerable women at an early stage is warranted. The objectives of this study were (1) to explore long-term psychological distress in women at risk for hereditary breast cancer adhering to regular surveillance, and (2) to identify women being vulnerable for long-term psychological distress, defined in terms of a multifactorial risk profile.Methods: General distress and cancer-related distress were assessed at baseline (T0) and after 5-8 years (T1) in 197 high-risk women adhering to breast cancer surveillance. Coping styles, occurrence of breast cancer in the family of origin, breast cancer risk perception, and frequency of breast self-examination, as assessed at T0, were examined as predictor variables for long-term distress (T1).Results: Across time, women reported a significant reduction in intrusion and avoidance. Intrusion levels were increased among women who had lost a first-degree relative to breast cancer. Predictors of increased long-term distress were passive and palliative coping styles, excessive breast self-examination, and overestimation of breast cancer risk. On the other hand, coping through fostering reassuring thoughts was predictive for decreased long-term distress.Conclusion: On the basis of the identified risk profile, it is possible to identify vulnerable women at an early stage, who then may be offered additional and individually tailored support. Copyright (C) 2012 John Wiley & Sons, Ltd.