Spin glasses, error correcting codes, and synchronization of human stem cell organoids.

Spin glasses, error correcting codes, and synchronization of human stem cell organoids.
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旋转玻璃、纠错码和人类干细胞类器官的同步。

DOI:
10.1016/j.cell.2023.01.006
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发表时间:
2023
期刊:
影响因子:
64.5
通讯作者:
Thomson,Matt
Thomson,Matt
中科院分区:
生物学1区
文献类型:
--
作者:
Thomson,Matt

文献摘要

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磁自旋、摆钟和萤火虫在被安排成空间耦合和相互作用的个体群体时,都能自我组织成连贯的集体。Ramanathan和他的同事证明,人类干细胞类器官的空间耦合在发育转变过程中诱导了连贯的进展,从而可以解剖人类发育背后的分子电路。
Magnetic spins, pendulum clocks, and fireflies all self-organize into coherent collectives when arranged into groups of spatially coupled and interacting individuals. Ramanathan and colleagues demonstrate that spatial coupling of human stem cell organoids induces coherent progression through developmental transitions, allowing the dissection of molecular circuits underlying human development.