A zoonotic human infection with simian malaria, Plasmodium knowlesi, in Central Kalimantan, Indonesia.
A zoonotic human infection with simian malaria, Plasmodium knowlesi, in Central Kalimantan, Indonesia.
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DOI：
10.1186/s12936-016-1272-z
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发表时间：
2016-04-16
期刊：
影响因子：
3
通讯作者：
Syafruddin D
中科院分区：
文献类型：
--
作者：
Setiadi W;Sudoyo H;Trimarsanto H;Sihite BA;Saragih RJ;Juliawaty R;Wangsamuda S;Asih PB;Syafruddin D
印度尼西亚群岛是疟疾的地方病。虽然恶性疟原虫和间日疟原虫是疟疾病例最常见的原因，但疟疾和卵形疟原虫也存在于某些地区。在2004年的色拉越研究之后，人畜共患疟疾病例刚刚引起公共卫生界的关注。然而，印度尼西亚的人畜共患病例仍未得到报告；2010年仅发表了一份南加里曼丹诺氏疟疾报告。报道了印度尼西亚中加里曼丹一家木炭开采公司的一名工人感染诺氏疟原虫的病例。这名工人在参观了一片正在砍伐并改建为新采矿点的低地森林后发烧。这项研究通过聚合酶链式反应扩增和桑格DNA测序证实了一起人畜共患感染，该DNA编码线粒体细胞色素C氧化酶亚基I(MtCOI)。
The Indonesian archipelago is endemic for malaria. Although Plasmodium falciparum and P. vivax are the most common causes for malaria cases, P. malariae and P. ovale are also present in certain regions. Zoonotic case of malaria had just became the attention of public health communities after the Serawak study in 2004. However, zoonotic case in Indonesia is still under reported; only one published report of knowlesi malaria in South Kalimantan in 2010. A case of Plasmodium knowlesi infection in a worker from a charcoal mining company in Central Kalimantan, Indonesia was described. The worker suffered from fever following his visit to a lowland forest being cut and converted into a new mining location. This study confirmed a zoonotic infection using polymerase chain reaction amplification and Sanger sequencing of plasmodial DNA encoding the mitochondrial cytochrome c oxidase subunit I (mtCOI).