Cellular DNA amounts of squamous cell carcinomas of the head and neck region in relation to prognosis
Cellular DNA amounts of squamous cell carcinomas of the head and neck region in relation to prognosis
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头颈部鳞状细胞癌的细胞DNA量与预后的关系
DOI：
10.1288/00005537-198209000-00018
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发表时间：
1982
期刊：
影响因子：
--
通讯作者：
L. Holm
中科院分区：
文献类型：
--
作者：
L. Holm
本文应用细胞光度法测定了45例头颈部鳞状细胞癌的单个肿瘤细胞中Feulgen DNA含量。发现11种癌具有DNA值的主要二倍体分布，而其余34种癌为非二倍体。在11个肿瘤中-与二倍体肿瘤不完全相同- 50%或更少的恶性细胞具有超过模式二倍体值（DNAG 1 + 2 S.D.）的DNA值，而34个具有较高的DNA值。
Cytophotometric measurements of Feulgen DNA content were made in individual tumor cells from 45 patients with squamous cell carcinomas of the head and neck region. Eleven carcinomas were found to have a predominantly diploid distribution of DNA values, while the remaining 34 carcinomas were non‐diploid. In 11 of the tumors — not entirely identical with the diploid tumors — 50% or less of the malignant cells had DNA values exceeding the modal diploid value (DNAG1 + 2 S.D.), whereas 34 had higher DNA values.