RESERVE ALBUMIN BINDING-CAPACITY, SALICYLATE SATURATION INDEX, AND RED-CELL BINDING OF BILIRUBIN IN NEONATAL JAUNDICE
RESERVE ALBUMIN BINDING-CAPACITY, SALICYLATE SATURATION INDEX, AND RED-CELL BINDING OF BILIRUBIN IN NEONATAL JAUNDICE
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DOI：
10.1136/adc.48.5.393
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发表时间：
1973-01-01
影响因子：
5.2
通讯作者：
BRATLID, D
中科院分区：
文献类型：
--
作者：
BRATLID, D
本文分析了72例新生儿的105份血标本，其中大多数为溶血性黄疸，用HBABA法测定了储备白蛋白结合力、水杨酸饱和指数和红细胞胆红素结合率。2例有胆红素脑病临床症状的婴儿有异常大量的红细胞结合胆红素，尽管HBABA结合能力和水杨酸饱和指数并不提示胆红素脑病的风险。另一方面，48个其他样品显示饱和指数的“风险值”，2个其他样品显示用HBABA方法判断的这种值。这些调查结果之间的差异进行了讨论。提示红细胞结合胆红素测定对新生儿黄疸，特别是提示性核黄疸有一定的临床价值。
105 blood samples from 72 infants, mostly with jaundice due to haemolytic disease, were analysed for reserve albumin binding capacity (HBABA method), salicylate saturation index (SI), and red cell binding of bilirubin. 2 infants with clinical symptoms of bilirubin encephalopathy had abnormally large amounts of red cell bound bilirubin, though the HBABA binding capacity and salicylate saturation index did not suggest a risk of bilirubin encephalopathy. On the other hand, 48 of the other samples showed `risk values' for saturation index and 2 of the other samples showed such values as judged by the HBABA method. The discrepancies between these findings are discussed. It is suggested that determination of red cell bound bilirubin may have clinical value in patients with neonatal jaundice, especially in cases of suggested kernicterus.