Structure and mechanical properties of β-TCP scaffolds prepared by ice-templating with preset ice front velocities
Structure and mechanical properties of β-TCP scaffolds prepared by ice-templating with preset ice front velocities
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DOI：
10.1016/j.actbio.2014.08.020
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发表时间：
2014-12-01
影响因子：
9.7
通讯作者：
Mueller, Frank A.
中科院分区：
文献类型：
--
作者：
Flauder, Stefan;Gbureck, Uwe;Mueller, Frank A.
通过对水基β -磷酸三钙（β - tcp）悬浮液进行定向凝固，成功制备出具有典型片状、排列、连续孔隙结构的各向异性支架。可调孔隙率从49%到82%，可调孔径从8到50 μ m，连接陶瓷细胞的壁厚从4到30 μ m。相关抗压强度从0.4 MPa(82%孔隙率，低凝固速度10。μ m s(-1) ~ 40 MPa（孔隙率49%，高凝固速度30 μ m s(-1)）。在一定孔隙率下，由于结构变化，随着凝固速度的增加，抗压强度增加了两倍以上。因此，控制结构尺寸的关键，除了通过初始悬浮液中的含水量来控制孔隙率之外，还在于控制凝固速度。本文采用热传导方程的解析解作为控制凝固过程中凝固速度的一种新方法。阐明并讨论了加工条件与组织、组织与力学性能之间的关系。(C) 2014材料学报Elsevier Ltd.出版。版权所有。
Anisotropic scaffolds with the typical structure of lamellar, aligned and continuous pores were successfully achieved by the directional solidification of water-based beta-tricalcium phosphate (beta-TCP) suspensions. Adjustable porosities from 49 to 82%, tunable pore widths from 8 to 50 mu m and linked ceramic cells with wall thicknesses from 4 to 30 lam were obtained. Correlated compressive strengths reached from 0.4 MPa (82% porosity, low solidification velocity of 10.mu m s(-1)) to 40 MPa (49% porosity, high solidification velocity of 30 mu m s(-1)). At a given scaffold porosity, the compressive strength increased by more than twofold with increasing solidification velocity due to attendant structural changes. Thus, the key to controlling structural sizes, besides the trivial control of porosity through the water content in the initial suspension, is to control the solidification velocity. In this study, an analytical solution of the heat conduction equation was used as a novel approach to control the solidification velocity during the process. The relationships between processing conditions and resulting structure as well as between structure and mechanical properties were elucidated and discussed. (C) 2014 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.