Facilitating Biomimetic Syntheses of Borrerine Derived Alkaloids by Means of Flow-Chemical Methods
Facilitating Biomimetic Syntheses of Borrerine Derived Alkaloids by Means of Flow-Chemical Methods
复制标题
DOI：
10.1071/ch14530
复制
发表时间：
2015-01-01
影响因子：
1.1
通讯作者：
Ley, Steven V.
中科院分区：
文献类型：
--
作者：
Kamptmann, Sonja B.;Ley, Steven V.
流动化学在当今合成化学中得到了广泛的应用，并越来越多地应用于复杂的天然产物的合成。然而，到目前为止，流动化学还没有在仿生合成领域找到一席之地。在这里，我们展示了冰片衍生生物碱的合成，表明我们可以利用流动中的仿生原理在一步内制备复杂的结构。
Flow chemistry is widely used nowadays in synthetic chemistry and has increasingly been applied to complex natural product synthesis. However, to date flow chemistry has not found a place in the area of biomimetic synthesis. Here we show the syntheses of borrerine derived alkaloids, indicating that we can use biomimetic principles in flow to prepare complex architectures in a single step.