The role of CD4 T cell help for CD8 CTL activation.

The role of CD4 T cell help for CD8 CTL activation.
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DOI:
10.1016/j.bbrc.2009.04.134
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发表时间:
2009-07
影响因子:
3.1
通讯作者:
S. Zhang;Hong-Jun Zhang;Jia-hong Zhao
S. Zhang;Hong-Jun Zhang;Jia-hong Zhao
中科院分区:
生物学4区
文献类型:
--
作者:
S. Zhang;Hong-Jun Zhang;Jia-hong Zhao

文献摘要

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CD4 T细胞在CD8 T细胞应答的启动和持续中起重要作用。在这篇综述中,我们报告和评估的机制,CD4 T细胞有助于激活CD8 T细胞和信号通路的下游事件后,CD4 T细胞的帮助。
CD4 T cells play an important role in the initiation and persistence of CD8 T cells responses. In this review, we report on and evaluate the mechanisms by which CD4 T cells contribute to activation of CD8 T cells and the signal pathways of the down-streaming events after CD4 T cell help.